產(chǎn)品詳情
Cat#：196P01
序列（三字母）：H-Lys-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Ala-Ala-Gly-Ala-Val-Val-Gly-Gly-Leu-Gly-OH trifluoroacetate salt
序列（單字母）：KTNMKHMAGAAAAGAVVGGLG
類似名：Prion Protein Fragment (106-126), human
分子式：C??H???N??O??S?
分子量：1912.27
CAS#：148439-49-0
合成方法：Synthetic
存儲(chǔ)條件：-20 ± 5 °C
應(yīng)用：Apoptosis & Necrosis
描述：An altered form of the large cellular prion protein accumulates in the CNS of patients with neurodegenerative disorders, and its protease-resistant core aggregates extracellularly into amyloid fibrils. This process is accompanied by nerve cell loss. The 21-peptide KTNMKHMAGAAAAGAVVGGLG is used as a model to investigate neurodegeneration in prion diseases. Prion Protein (106-126) forms fibrils in vitro and causes apoptotic cell death in neuron culture. Its neurotoxicity depends on the presence of microglia and is induced by microglia. It could be demonstrated that KTNMKHMAGAAAAGAVVGGLG is able to bind to DNA, a circumstance which led to the assumption that the integral protein could also bind to DNA under appropriate solution conditions.
1）通過電話（+86-(0)-18115476705）郵件（sales@tgpeptide.com）聯(lián)系我們；
2）提供合成多肽的具體需求，包括序列、質(zhì)量和純度，技術(shù)部門評(píng)估后給與報(bào)價(jià)。
3）簽訂多肽合成合同，交付合成預(yù)付款，科研機(jī)構(gòu)先使用再付款！
4）合成過程定期跟您匯報(bào)合成進(jìn)度及情況；
5）根據(jù)合同內(nèi)容，隨貨提供發(fā)票；
6）如因本公司原因不能交貨或合成失敗，退還所有合成款！
Copyright ?2020 南京肽谷生物科技有限公司 備案號(hào)：蘇ICP備19062824號(hào)-1 網(wǎng)站地圖
